Rank	Pitcher	YEAR	AVG
1	Sad Sam Jones	1922	726.9
2	Sad Sam Jones	1921	723.0
3	Eppa Rixey	1921	712.9
4	Eppa Rixey	1922	676.8
5	Stan Coveleski	1926	561.2
6	Dolf Luque	1924	546.6
7	Dolf Luque	1923	512.6
8	Eppa Rixey	1924	439.7
9	Greg Maddux	1995	406.1
10	Pete Donohue	1926	394.1
11	Pete Donohue	1925	385.4
12	Bob Veale	1965	383.1
13	Eppa Rixey	1928	368.7
14	Dean Chance	1964	342.8
15	Greg Maddux	1994	336.9
16	Cy Blanton	1936	334.3
17	Eppa Rixey	1929	333.3
18	Sheriff Blake	1928	331.1
19	Herb Pennock	1928	315.9
20	Pete Donohue	1923	313.6
21	Roger Clemens	1998	312.8
22	Dean Chance	1965	312.6
23	Bob Veale	1966	309.4
24	Kevin Brown	1998	307.5
25	Eppa Rixey	1923	306.8
26	Danny MacFayden	1936	296.1
27	Pete Donohue	1924	295.4
28	Kevin Brown	1997	286.2
29	Danny MacFayden	1937	285.7
30	Andy Pettitte	1998	284.0
31	Andy Pettitte	1997	281.1
32	Mel Harder	1935	280.2
33	Lee Meadows	1924	278.8
34	Joe Magrane	1990	278.2
35	Eppa Rixey	1925	278.0
36	Lee Meadows	1923	273.7
37	Roger Clemens	1997	269.4
38	Mike Hampton	2000	265.3
39	Sheriff Blake	1929	265.2
40	Kevin Brown	1999	262.9
41	Greg Maddux	1997	260.1
42	Greg Maddux	1996	259.7
43	Waite Hoyt	1922	256.3
44	Willis Hudlin	1928	254.9
45	Max Lanier	1944	252.0
46	Kevin Appier	1993	248.2
47	Tommy John	1980	247.2
48	Claude Osteen	1966	246.7
49	Kevin Appier	1995	245.1
50	Kevin Brown	1996	245.0
51	Greg Maddux	1998	244.8
52	Danny MacFayden	1938	244.6
53	Paul Derringer	1933	243.5
54	Tim Lincecum	2009	242.0
55	Pedro Martinez	2000	239.4
56	Danny MacFayden	1931	238.5
57	Lefty Gomez	1938	237.4
58	George Mogridge	1924	236.7
59	Tommy John	1979	235.6
60	Claude Osteen	1967	235.0
61	Carlos Zambrano	2004	232.5
62	Mel Parnell	1949	232.1
63	Greg Maddux	1993	230.1
64	Storm Davis	1984	229.2
65	Hal Newhouser	1945	228.5
66	Earl Hamilton	1921	228.4
67	Dutch Ruether	1921	228.1
68	Paul Derringer	1934	227.7
69	Roger Clemens	1991	226.5
70	Mike Garcia	1955	224.8
71	Mark Gubicza	1989	224.2
72	Dolf Luque	1925	224.1
73	George Pipgras	1929	222.3
74	Claude Passeau	1945	221.5
75	Bob Gibson	1970	220.0
76	Mike Garcia	1954	217.6
77	Randy Jones	1979	216.7
78	Mel Harder	1936	215.9
79	Mort Cooper	1944	214.4
80	Brandon Webb	2008	213.8
81	Mike Garcia	1952	212.8
82	Randy Jones	1978	212.3
83	Johnny Vander Meer	1943	212.0
84	Lou Fette	1938	211.8
85	Brandon Webb	2007	211.5
86	Nolan Ryan	1978	210.6
87	Dean Chance	1963	210.3
88	Hal Newhouser	1946	209.2
89	Si Johnson	1932	208.5
90	Watty Clark	1932	207.0
91	Jack Quinn	1928	206.9
92	Gary Peters	1964	206.6
93	Lefty Grove	1930	206.0
94	Tom Glavine	1993	205.1
95	Pedro Martinez	1999	205.0
96	Johnny Morrison	1924	204.9
97	Mel Harder	1934	204.8
98	Danny Jackson	1993	204.7
99	Roy Halladay	2003	204.6
100	Mark Gubicza	1988	204.5